Research
Dr. Kathrin Spendier CURRICULUM VITAE (CV)
Research Interests
Experimental
· Role of cell surface curvature in disease models
· Metallic nanoparticles for biomedical application
· Cell membrane protein dynamics
Theoretical
· Kinetic theory of particle nucleation
· Reaction-Diffusion
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Peer Reviewed Publications
1) Amanda Carroll-Portillo, Kathrin Spendier, Janet Pfeiffer, Gary Griffiths, Haitao Li, Keith A. Lidke, Janet M. Oliver, Diane S. Lidke, James L. Thomas, Bridget S. Wilson, and Jerilyn A. Timlin, “Formation of a Mast Cell Synapse: FcεRI Membrane Dynamics upon Binding Mobile or Immobilized Ligands on Surfaces” Journal of Immunology, Volume 184, Issue 3, 2010. (link)
2) Kathrin Spendier, Amanda Carroll-Portillo, Keith A. Lidke, Bridget S. Wilson, Jerilyn A. Timlin, and James L. Thomas, “Distribution and Dynamics of Rat Basophilic Leukemia Immunoglobulin E Receptors (FcεRI) on Planar Ligand-Presenting Surfaces” Biophysical Journal, Volume 99, Issue 2, 2010. (link)
3) Kathrin Spendier and James L. Thomas, “Image Correlation Spectroscopy of Randomly Distributed Disks“ Journal of Biological Physics, Volume 37, Issue 4, 2011. (link)
4) Kathrin Spendier, Diane S. Lidke, Keith A. Lidke and James L. Thomas, “Single-particle tracking of immunoglobulin E receptors (FcεRI) in micron-sized clusters and receptor patches“ FEBS Letters, Volume 586, Issue 4, 2012. (link)
5) Kathrin Spendier and James L. Thomas, “Spatial Patterns in Mast Cell Activation“ in Mast Cells: Phenotypic Features, Biological Functions, and Role in Immunity, Nova Science Publishers, 2013.
6) Kathrin Spendier and V.M. Kenkre, “Analytic Solutions for Some Reaction-Diffusion Scenarios” J. Phys. Chem. B, Volume 117, Issue, 49, 2013. (link)
7) Kathrin Spendier, Satomi Sugaya, and V.M. Kenkre, “Reaction-Diffusion Theory in the Presence of an Attractive Harmonic Potential” Phys. Rev. E, Volume 88, 062142, 2013. (link)
8) C. Aidalaj, L. Anaya, E. Andersse, A. Bambaugh, A. Barron, J.G. Boissevain, J. Bok, S. Boose, M.L. Brooks, S. Butsyk, M. Cepeda, P. Chacon, S. Chacon, L. Chavez,T. Cote, C. D’Agostino, A. Datta , K. DeBlasio, L. DelMonte, E.J. Desmond,J.M. Durham, D. Fields, M. Finger, C. Gingu, B. Gonzales, J.S. Haggerty, T. Hawke, H.W. van Hecke, M. Herron, J. Hoff, J. Huang, X. Jiang, T. Johnson, M. Jonas, J.S. Kapustinsky, A. Key, G.J. Kunde, J. Kurtz, J. LaBounty, D.M. Lee, K.B. Lee, M.J. Leitch, M. Lenz, W. Lenz, M.X. Liu, D. Lynch, E. Mannel, P.L. McGaughey, A. Meles, B. Meredith, H. Nguyen, E. O’Brien, R. Pak, V. Papavassiliou, S. Pate, H. Pereira, G.D.N. Perera, M. Phillips, R. Pisani, S. Polizzo, R.J. Poncione, J. Popule, M. Prokop, M.L. Purschke, A.K. Purwar, N. Ronzhina, C.L. Silva, M. Slunečka, R. Smith, W.E. Sondheim, K. Spendier, M. Stoffer, E. Tennant, D. Thomas, M. Tomášek, A. Veicht, V. Vrba, X.R. Wang, F. Wei, D. Winter, R. Yarema, Z. You, I. Younus, A. Zimmerman, T. Zimmerman, “The PHENIX Forward Silicon Vertex Detector” Nuclear Instruments and Methods in Physics Research A, Volume 755, 44-61, 2014 (link).
9) R. S. Kalkur, A. C. Ballast, A. R. Triplett, K. Spendier, “Effects of Deuterium Oxide on Cell Growth and Vesicle Speed in RBL-2H3 Cells ” PeerJ 2:e553, 2014 (link).
10) K. Spendier, “N-terminal amphipathic helix of Amphiphysin can change the spatial distribution of immunoglobulin E receptors (FcεRI) in the RBL-2H3 mast cell synapse ” Results in Immunology, Volume 6, 1-4, 2016 (link).
11) V. Kravets, Z. Almemar, K. Jiang, K. Culhane, R. Machado, G. Hagen, A. Kotko, I. Dmytruk, K. Spendier, A. Pinchuk, “Imaging of biological cells using luminescent silver nanoparticles” Nanoscale Research Letters, 11:30, 2016 (link).
12) M. Chase, K. Spendier, and V.M. Kenkre, “Analysis of Confined Random Walkers with Applications to Processes Occurring in Molecular Aggregates and Immunological Systems ” accepted J. Phys. Chem. B, 120:3072-3080, 2016 (link).
13) N. D. Zameroski, K. Spendier, D. Kerwin, M.Spencer, J. M. Parson, and C. Hettler, ” Investigations into 25- and 30-µm-Thick Glass Capacitors at 23oC and 235oC and Area Dependence of Dielectric Strength of Alkali-Free Schott Inc. AF32 ECO Glass,” IEEE Transactions on Plasma Sciences, 44 (6), 973-979 2016 (link).
14) E. C. Economou, S. Marinelli, M. C. Smith, A. A. Routt, V. V. Kravets, H. W. Chu, K. Spendier, and Z. J. Celinski, “Magnetic Nanodrug Delivery Through the Mucus Layer of Air-Liquid Interface Cultured Primary Normal Human Tracheobronchial Epithelial Cells,” BioNanoScience, 2016 (link).
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Peer Reviewed Conference Proceedings
1) K. Jiang, K. Spendier, and A. O. Pinchuk, “Laser-directed deposition of silver nanostructures”, Plasmonics: Metallic Nanostructures and Their Optical Properties XII: Proc. of SPIE Vol. 9163, 2014 (link).
2) K. M. Culhane, K. Spendier, and A. O. Pinchuk, Functionalized fluorescent silver nanoparticle surfaces for novel sensing and imaging techniques, SPIE Vol. 9481, Image Sensing Technologies: Materials, Devices, Systems, and Applications II, pp. 948106-948106-9, 2015 (link).